Integrated ON/OFF Protocol

With explanations of what will be eliminated, how, realistic estimates, synergies and monitoring.


:counterclockwise_arrows_button: General structure of the cycle

  • 1 day ON = chelation + mobilization
  • 1 day OFF = rest + regeneration + replenishment

Recommended frequency: Repeat the cycle 3–9 times
( 12–21 days ) as an intensive treatment.
Then proceed to the maintenance phase.


:bullseye: What is eliminated/mobilized and by what method

Heavy metals

Lead (Pb), cadmium (Cd), aluminum (Al), arsenic (As), mercury (Hg)

EDTA (oral/IV)
Extracellular chelation: captures metals in blood/plasma and free calcium; promotes renal excretion.
Typical estimated rate: plasma reduction in weeks; accumulation in urine 24–48h after dose.

Metals in soft tissues

Hg, Pb, Cd, As

DMSA + DMPS
Intracellular and extracellular chelation: mobilizes metals from organs/tissues into the blood, then renal elimination.
Typical estimated rate: increase in urinary excretion at 24–48 hours; decrease in tissue after a full cycle (weeks).

Free radicals / oxidative stress

ALA + natural antioxidants
(turmeric, selenium, glutathione via precursors)

Neutralization of ROS, mitochondrial and cellular protection against “toxic rebound”.
Typical estimated speed: immediate action, mitigation of acute effects.

Biofilms / latent infections / intracellular pathogens

Colloidal silver + rectal ozone therapy + immune support

Antimicrobial action, biofilm disruption, deep disinfection.
Typical estimated rate: improvement in microbial load in 3–7 days after the ON phase.

“Estimated typical rate” is based on medical chelation, toxicology and detoxification studies: clearly varies according to body load, kidney/liver function, adherence, etc.


:fire: PHASE 1 — DAYS ON

Mobilization + Deep chelation

Objective: to mobilize metals, toxins and biofilms; to activate cellular energy and systemic detox.

:eight_o_clock: 08:00 — Nano colloidal gold (10 ml sublingual)

  • Cellular and bioelectrical stabilization
  • Prepare your nervous system for MWO

:eight_thirty: 08:15 — MWO v999 (21 minutes)

  • Harmonic vibrational stimulation
  • Opening of ion channels
  • Mitochondrial activation

:nine_o_clock: 09:00 — Restructured water + light breakfast

  • Metabolic activation without digestive excess
  • Structured water = better cellular transport

:nine_thirty: 09:30 — 1 EDTA capsule (500 mg)

  • Extracellular chelation of metals (lead, cadmium, aluminum)
  • Initiate renal excretion

:one_o_clock: 13:00 — Food rich in raw turmeric + black pepper

  • You can use capsules (3Ă—) or add them to the dish
  • Powerful anti-inflammatory + liver support Phase II

:five_o_clock: 17:00 — 1 ALA + DMSA capsule + whole wheat bread + olive oil

  • ALA enters mitochondria → mobilizes mercury / improves redox
  • DMSA: intra- and extracellular chelation without toxicity

:eight_o_clock: 8:00 PM — 1 DMPS capsule

  • Final cleaning of remaining metals
  • Stimulates renal/hepatic elimination

:person_in_lotus_position: PHASE 2 — DAYS OFF

Recovery + Replacement + Regeneration

Objective: to replenish minerals, regenerate tissues, modulate inflammation, and prevent rebound effects.

:eight_o_clock: 08:00 — Nano colloidal gold (10 ml sublingual)

  • Maintains cellular activation without chelation

:nine_o_clock: 08:30 — Restructured water + genuine B complex + magnesium (300 mg)

  • Nutritional support for the nervous system
  • Magnesium = antiarrhythmic, relaxant, cellular cofactor

:one_o_clock: 13:00 — Food + shot of isotonic seawater + Vitamin K2 MK-7 (1 capsule)

  • It replenishes calcium, zinc, selenium, and directs calcium to bones.
  • K2 prevents arterial and mammary calcification

:four_o_clock: 16:00 — Natural E Complex (400 IU) + Natural Vitamin A + Essential Amino Acids

  • Epithelial, hepatic, mammary and mitochondrial antioxidant regeneration
  • Essential amino acids = raw material for regeneration

:five_o_clock: 17:30 — Rectal ozone (low dose, 1 to 3 times daily)

  • Improves cellular oxygenation
  • Stimulates good microbiota
  • It helps in liver/intestinal detoxification phases

:sunset: 19:00 — Systemic enzymes (bromelain / serrapeptase / nattokinase) in fasting

  • Microbiofilm removal
  • Lymphatic and breast drainage support
  • Dissolution of subclinical fibrosis

:crescent_moon: 22:00 — Nano colloidal silver (10 ml)

  • Antibacterial, antiviral action
  • Especially useful after chelation (biofilms released)

:counterclockwise_arrows_button: General cycle

  • Day 1: Deep Detox → ON Day
  • Day 2: Repair and replacement → OFF Day
  • Day 3: Deep Detox → ON Day
  • Day 4: Repair and Replacement → OFF Day

And so in continuous alternation until completing 14–21 days .


:shield: Ongoing support

Throughout the ON/OFF protocol, the following is maintained:

  • Restructured water: 2 L/day minimum
  • Magnesium: 300–500 mg/day (bisglycinate or chloride)
  • K2 MK-7: 2Ă— per day (OFF), 1Ă— on
  • Seawater shot: 1x per day (with food)
  • Milk thistle (Silymarin): 1 capsule with food (daily)
  • NAC (N-acetylcysteine): 600–1200 mg/day
  • Rectal ozone: 1–3 times per day (in OFF mode)

:clipboard: Optional monitoring

  • Creatinine/urea levels (kidney function)
  • Minerals in blood (Ca, Mg, Zn, K)
  • 24h urine test for heavy metals + minerals
  • Breast thermography/ultrasound (fibrosis/inflammation)
  • Symptom questionnaire (energy, digestion, inflammation, mental clarity)

:gear: PHASE 3 — Maintenance, Deep Repair and Monitoring

Main objectives: consolidate changes, allow deep tissue regeneration, prevent rebounds, long-term monitoring.

Typical interventions

  • Low doses of mild chelating agents if there is re-exposure
  • Daily antioxidants (ALA, NAC, selenium, vitamin E)
  • Balanced mineral supplementation (Mg, Zn, Se, occasional seawater)
  • Anti-inflammatory diet, low in toxic loads, rich in nutrients, antioxidants, phytochemicals
  • Lifestyle: rest, good sleep hygiene, moderate exercise, periodic dry sauna (1-2 times/week), hydrotherapy, lymphatic drainage if appropriate
  • Periodic assessments (every 3-6 months): metal analysis, mineral profile, renal, hepatic, oxidative markers, cellular function

:pushpin: What to document and present to the team/patient

  1. Goal of the cycle (detox → repair → maintenance)
  2. Complete ON/OFF Calendar
  3. What is eliminated — with estimated excretion data per chelating agent
  4. What is replenished — minerals, antioxidants, essential nutrients
  5. Potential risks and mitigation (hypocalcemia, renal stress, demineralization, toxic rebound)
  6. Plan of analyses and controls — before the protocol, during (half cycle), after, and in maintenance
  7. Informed consent: clearly explain expected benefits, uncertainties, risks, and the need for clinical follow-up.

:white_check_mark: Why this approach is sound from a scientific/integrative point of view

  • Adaptive chelation: using different chelating agents with different affinities allows for the mobilization of more types of toxins — not depending on just one.
  • Balance between cleansing and repair: it’s not just about “detoxifying,” but also about “repairing” — mitochondria, antioxidants, minerals, liver/kidney function.
  • Cycles + rest periods: prevent overload, allow homeostasis, and reduce the risk of mineral imbalance or kidney toxicity.
  • Rigorous clinical monitoring: with analyses and biomarkers, it allows adjustment according to the patient, not a “generic dose for everyone”.

:microscope: Clinical Monitoring Module

1. What tests to do and how to request them

2. How to interpret the results

3. What to replace if there are alterations

4. When to pause, reduce, or adjust the protocol


:yellow_circle: A. Liver function

Recommended tests

  • ALT (GPT)
  • AST (GOT)
  • GGT
  • Alkaline phosphatase (ALP)
  • Total and direct bilirubin
  • Albumin

Key interpretation

  • ALT/AST > 3Ă— normal value → Stop 3–5 days / high liver stress
  • GGT > 80 U/L → Reduce DMSA/DMPS dose / possible hepatic congestion
  • Direct bilirubin > 1.2 mg/dL → Evaluate liver + gallbladder / hepatic retention or blockage
  • Albumin < 3.5 g/dL → Consider protein support / catabolism or inflammation

Recommended support

  • Milk thistle (Silymarina 200–400 mg/day)
  • N-Acetyl Cysteine ​​(NAC 600–1200 mg/day)
  • Betaine + taurine (supports methylation and bile)

:blue_circle: B. Renal function and excretion

Key analytics

  • Creatinine
  • Urea
  • Glomerular Filtration Rate (eGFR)
  • Proteinuria/Microalbuminuria

Alert values

  • Creatinine > 1.2 mg/dL (women), > 1.4 (men) → Pause chelation for 2–3 days
  • eGFR < 60 ml/min/1.73 m² → Monitor, reduce EDTA
  • Urea > 50 mg/dL → Monitor hydration, renal support

Recommended support

  • Restructured water + daily seawater shot
  • Magnesium (300–500 mg/day)
  • Infusion of dandelion, nettle or horsetail

:magnet: C. Mineral and Trace Element Panel

Request as

  • “Blood Minerals” or “Trace Element Profile”
  • 24-hour urine mineral analysis (after DMSA/EDTA)

Essential parameters

  • Calcium (Ca)
  • Magnesium (Mg)
  • Potassium (K)
  • Zinc (Zn)
  • Selenium (Se)
  • Sodium (Na)
  • Copper (Cu)
  • Phosphorus (P)
  • Lithium (optional)
  • Manganese (Mn)

Practical interpretation

  • Calcium < 8.6 mg/dL → Add bioavailable calcium (citrate 500 mg/day) + K2
  • Calcium > 10.5 mg/dL → Discontinue K2
  • Magnesium < 1.7 mg/dL → Mg bisglycinate 300–500 mg/day
  • Magnesium > 2.5 mg/dL → Adjust if necessary
  • Zinc < 65 µg/dL → Add Zn bisglycinate (25–30 mg/day)
  • Selenium < 60 µg/L → Add Se (100–200 mcg/day, selenomethionine)
  • Selenium > 150 µg/L → May be toxic
  • Potassium < 3.5 mmol/L → Add potassium-rich foods/supplements with caution
  • Potassium > 5.2 → Pause any intake

:red_circle: D. Heavy metals

Specific analytics

  • “Heavy metals in urine 24 h post-chelation”
  • After 500 mg EDTA / 250 mg DMSA
  • Measure: Pb, Hg, Cd, Al, Ni, As, Ti

Specialized laboratories (Spain/EU)

  • Echevarne
  • Synlab
  • Bioclinic Lab
  • Doctor’s Data (USA) — if you have access

Useful interpretation

  • If after 2–3 cycles there are still high metal levels: continue with ON phase
  • If there is no longer a detectable load: reduce frequency and enter maintenance phase (1 ON every 3 days)

:test_tube: E. Additional functional biomarkers

  • Homocysteine ​​→ Evaluates methylation status / B12 / folate
  • High-sensitivity PCR (C-Reactive Protein) → Detects subclinical inflammation
  • Thyroid profile (TSH, free T3, free T4) → Due to the influence of iodine and metals on the thyroid
  • Ferritin → Alert for inflammation or latent anemia

:lotion_bottle: Safe replenishment based on results

  • Magnesium → Mg bisglycinate 300–500 mg (best at night)
  • Zinc → Zn bisglycinate or picolinate 25 mg/day
  • Calcium → Calcium citrate + K2 (never alone)
  • Selenium → Selenomethionine 100–200 mcg/day
  • Glutathione → NAC 600–1200 mg or liposomal glutathione
  • Amino acids → MAP or plant-based formula 5–10 g daily
  • Electrolytes → Isotonic seawater 1x/day in food

:stop_sign: When to stop or adjust the protocol

  • ALT/AST > 3Ă— normal value → Stop DMSA/DMPS for 3 days
  • Creatinine > 1.3 / GFR < 60 → Pause EDTA, reinforce renal support
  • Calcium < 8.5 mg/dL + symptoms → Add calcium, temporarily pause K2
  • Dizziness, arrhythmias, sudden fatigue → Assess electrolytes and renal function — pause for 48 hours
  • Severe Herxheimer’s (fever, vomiting, diarrhea) → Double hydration + rest for 24–48 hours + rectal ozone

Detox , Quantum Therapies